Of the four subjects who received Fildena 100 mg in the

18 Jul 2018 10:43
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In the following patients: age > 65 years, hepatic impairment (e.g., cirrhosis ), severe renal impairment (e.g., creatinine clearance < 30 mL/min), and concomitant use of erythromycin or strong CYP3A4 inhibitors, plasma levels of Fildena at 24 hours post dose have been found to be 3 to 8 times higher than those seen in healthy volunteers. Similar effects on blood pressure were noted with 25 mg, 50 mg and 100 mg of Fildena, therefore the effects are not related to dose or plasma levels within this dosage range. Single oral doses of Fildena (100 mg) administered to healthy volunteers produced decreases in sitting blood pressure (mean maximum decrease in systolic / diastolic blood pressure of 8.3/5.3 mmHg).

Decreased blood pressure, syncope , and prolonged erection were reported in some healthy volunteers exposed to high doses of Fildena (200-800 mg). In a drug-drug interaction study Fildena 50 mg given with alcohol 0.5 g/kg in which mean maximum blood alcohol levels of 0.08% was achieved, Fildena did not potentiate the hypotensive effect of alcohol in healthy volunteers see CLINICAL PHARMACOLOGY. STEWART: Meika Loe is a professor of sociology and anthropology at Colgate University and author of "The Rise of Fildena: How the Little Blue Pill Changed Sex in America." Thanks for taking the time, Meika.

Pfizer says 35 million men around the world have taken it. Here to talk about the cultural measure of that little blue pill is Meika Loe, a professor of sociology and anthropology at Colgate University, and the author of, "The Rise of Fildena: How the Little Blue Pill Changed Sex in America." Good morning, Meika. The active drug in Fildena, Pfizer was testing it as a cardiovascular drug for its ability to lower blood pressure, but it raised something else, earning it the nickname "the Pfizer Riser." So how did the researchers find out? Men who see good sex as being synonymous with the presence of an erection — any erection, no matter how emotionally disconnected from it they may be — are especially prone to developing a dependency on erectile dysfunction drugs, says Baum.

Residents of the village of Ringaskiddy in County Cork claim the fumes from the local Pfizer factory — which has long produced the erectile dysfunction drug — are arousing their menfolk, the Sunday Times reports. Though it proved to be an effective treatment for erectile dysfunction and pulmonary arterial hypertension (a type of high blood pressure), adverse side effects were soon reported. The class of drugs currently prescribed to treat male erectile dysfunction has been flagged for its potential to be included in new trials for anti-cancer drugs.

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